Intra Cytoplasmic Sperm Injection (ICSI)

ICSI is a micromanipulation procedure whereby a single sperm is injected into the single egg with the help of small micro needle with the help of robotic machine called micromanipulator. Super ovulation, follicular monitoring, ovum pick up is done like that in IVF. This technique may provide men who have very small amounts of sperm (too small for routine IVF) a chance to fertilize individual eggs. When the egg is fertilized, the embryo is inserted into the uterus.

ICSI can be used when:

  • The number of sperm available is too few to expect fertilization; ie very low sperm count & motility, 
  • Fertilization has not occurred in previous IVF cycles despite a high number of sperm being present; 
  • The only sperm available are those which have been collected direct from the testis. e.g. in cases of congenital absence of vas or obstructive azoospermia. 
  • Repeated IVF failures, 
  • If not enough eggs could be retrieved from the woman, as in woman with advance age and unexplained infertility cases
ICSI / IVF splits

sometimes, it is not possible to say in advance whether ICSI will be necessary to achieve fertilization of eggs. An ICSI / IVF split involve treating half of the eggs with ICSI and half with IVF. In this way we can find out if ICSI is really necessary while still ensure that if IVF does not work at least some fertilized eggs are available for transfer. An ICSI/IVF split is normally only done if 12 or more eggs are collected. If fewer eggs than this were collected then ICSI would be carried out on all the eggs.

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